Package: ondisc
Title: Algorithms and Data Structures for Large Single-Cell Expression
        Matrices
Version: 1.3.5
Depends: R (>= 4.1.0)
Authors@R: 
    c(person(given = "Timothy",
            family = "Barry",
            role = c("aut", "cre"),
            email = "tbarry@hsph.harvard.edu",
            comment=c(ORCID="0000-0002-4356-627X")),
      person(given = "Songcheng",
             family = "Dai",
             role = "ctb"),
      person(given = "Yixuan",
             family = "Qiu",
             role = "ctb"),
      person(given = "Eugene",
            family = "Katsevich",
            role = c("aut", "ths"),
            email = "ekatsevi@wharton.upenn.edu"))
Description: Single-cell datasets are growing in size, posing
        challenges as well as opportunities for genomics researchers.
        'ondisc' is an R package that facilitates analysis of
        large-scale single-cell data out-of-core on a laptop or
        distributed across tens to hundreds of processors on a cluster
        or cloud. In both of these settings, 'ondisc' requires only a
        few gigabytes of memory, even if the input data are tens of
        gigabytes in size. 'ondisc' mainly is oriented toward
        single-cell CRISPR screen analysis, but also can be used for
        single-cell differential expression and single-cell
        co-expression analyses. 'ondisc' is powered by several new,
        efficient algorithms for manipulating and querying large,
        sparse expression matrices.
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
LinkingTo: Rcpp, Rhdf5lib
biocViews: DataImport, SingleCell, DifferentialExpression, CRISPR
RoxygenNote: 7.3.2
Imports: crayon, data.table, methods, Rcpp, Rhdf5lib, dplyr, readr,
        Matrix
SystemRequirements: GNU make
Suggests: sessioninfo, knitr, R.utils, rmarkdown, testthat (>= 3.0.0)
Config/testthat/edition: 3
URL: https://timothy-barry.github.io/ondisc/,
        https://timothy-barry.github.io/sceptre-book/
BugReports: https://github.com/timothy-barry/ondisc/issues
VignetteBuilder: knitr
Config/pak/sysreqs: make libx11-dev
Repository: https://timothy-barry.r-universe.dev
Date/Publication: 2026-06-09 16:57:02 UTC
RemoteUrl: https://github.com/timothy-barry/ondisc
RemoteRef: HEAD
RemoteSha: 6f79c8492d85269528e6d0667780df2c0017c0ad
NeedsCompilation: yes
Packaged: 2026-06-18 09:08:23 UTC; root
Author: Timothy Barry [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-4356-627X>),
  Songcheng Dai [ctb],
  Yixuan Qiu [ctb],
  Eugene Katsevich [aut, ths]
Maintainer: Timothy Barry <tbarry@hsph.harvard.edu>